TEGASEROD MALEATE EXERTS ANTI-TUMOR EFFECTS ON PROSTATE CANCER VIA REPRESSING SONIC HEDGEHOG SIGNALING PATHWAY

Tegaserod maleate exerts anti-tumor effects on prostate cancer via repressing sonic hedgehog signaling pathway

Abstract Prostate cancer (PCa) is a highly common type of malignancy and affects millions of men in the world since it is easy to recur or emerge Nylon/Synthetic Headstalls therapy resistance.Therefore, it is urgent to find novel treatments for PCa patients.In the current study, we found that tegaserod maleate (TM), an FDA-approved agent, inhibited

read more


Precedence effect for specular and diffuse reflections

Studies on the precedence effect are typically conducted by presenting two identical sounds simulating direct sound and specular reflection.However, when a sound is reflected from irregular surface, it is redirect into many directions resulting in directional and temporal diffusion.This contribution Quick Start Overlay introduces a simulation of La

read more

Response of the Nigerian construction sector to economic shocks

The construction sector (CS) is an economic barometer that mirrors the state of the economy.Therefore, the construction sector is susceptible to economic impacts.This study investigated the impact of economic shocks (measured with the Gross Domestic Product (GDP)) on construction sector performance.The study used econometric methodology which invol

read more